Updates Adobe Flash for IE / Edge on Windows 10 1607
Server 2016 will only install the Flash Hotfix if the Remote Desktop Session Host (RDSH) role and its prerequisite roles/features are enabled. If these roles and features are not enabled, Server 2016 will return error code 2.
Error -2145124329 means the update does not apply. This means the conditions were met to run the patch however Windows states that the update can't be used. For example this error would be returned if a Windows 10 Preview OS has this patch deployed.